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    Adipocytes , also known as lipocytes and fat cells , are the cells that primarily compose adipose tissue , specialized in storing energy as fat. In cell culture , adipocytes can also form osteoblasts, myocytes and other cell types. There are two types of adipose tissue, white adipose tissue WAT and brown adipose tissue BAT , which are also known as white and brown fat, respectively, and comprise two types of fat cells. White fat cells contain a single large lipid droplet surrounded by a layer of cytoplasm , and are known as unilocular. The nucleus is flattened and pushed to the periphery.
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    The fat and the bad: Mature adipocytes, key actors in tumor progression and resistance

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    Fat grown in the lab - Research Highlights - Nature Middle East

    Thank you for visiting nature. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser or turn off compatibility mode in Internet Explorer. In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. Cyclooxygenases are known as important regulators of metabolism and immune processes via conversion of C20 fatty acids into various regulatory lipid mediators, and cyclooxygenase activity has been implicated in browning of white adipose tissues. TG mice fed a high-fat diet displayed marginally lower weight gain with less hepatic steatosis and a slight improvement in insulin sensitivity, but no difference in glucose tolerance.
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    Fat grown in the lab

    It is well known that fat cells can influence our sensitivity to insulin. Now, researchers at Karolinska Institutet in Sweden have discovered that there are three different subtypes of mature fat cells in white adipose tissue and that it is only one of these, called Adipo PLIN , that responds to insulin. The findings may be relevant for future treatments of metabolic diseases such as Type 2 diabetes. This could have implications for diseases such as obesity, insulin resistance and Type 2 diabetes.
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    Growing evidence has raised the important roles of adipocytes as an active player in the tumor microenvironment. In many tumors adipocytes are in close contact with cancer cells. They secrete various factors that can mediate local and systemic effects.
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